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. 1973 Aug;70(8):2313-6.
doi: 10.1073/pnas.70.8.2313.

Self-association of cholesterol in aqueous solution

Self-association of cholesterol in aqueous solution

M E Haberland et al. Proc Natl Acad Sci U S A. 1973 Aug.

Abstract

Cholesterol has a maximum solubility in aqueous solutions of 1.8 mug/ml or 4.7 muM. It undergoes a thermodynamically reversible self-association with a critical micelle concentration of 25 to 40 nM at 25 degrees . The cholesterol micelle is heterogeneous in size, probably rodlike in shape, and stabilized by an unusually high interaction energy between the aggregated monomers.

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References

    1. J Biol Chem. 1961 May;236:1372-9 - PubMed
    1. J Mol Biol. 1972 Jun 14;67(1):59-74 - PubMed
    1. Proc Natl Acad Sci U S A. 1970 Jul;66(3):1002-7 - PubMed
    1. J Biol Chem. 1967 Mar 25;242(6):1205-10 - PubMed
    1. Proc Natl Acad Sci U S A. 1957 Jul 15;43(7):581-8 - PubMed

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