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. 1974 May;71(5):1819-23.
doi: 10.1073/pnas.71.5.1819.

The amplified ribosomal DNA of dytiscid beetles

The amplified ribosomal DNA of dytiscid beetles

J G Gall et al. Proc Natl Acad Sci U S A. 1974 May.

Abstract

During oogenesis in many animals there is a massive extrachromosomal synthesis of the genes for ribosomal RNA. In Dytiscid beetles, as in the toad Xenopus, the amplified ribosomal DNA occurs as circular molecules of different sizes. The circles fall into size classes that are integral multiples of a unit circle. It is probable that the unit circle contains the coding sequence for one precursor ribosomal RNA molecule plus accompanying spacer sequences.

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