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. 1974 May;71(5):1677-80.
doi: 10.1073/pnas.71.5.1677.

The effect of erythropoietin on colonial growth of erythroid precursor cells in vitro

M C Cooper, J Levy, L N Cantor, P A Marks, R A Rifkind

The effect of erythropoietin on colonial growth of erythroid precursor cells in vitro

M C Cooper et al. Proc Natl Acad Sci U S A. 1974 May.

Abstract

A method is described for the colonial growth, in semi-solid medium, of erythropoietin-responsive erythroid cell precursors. The erythroid cell precursors were isolated by immune hemolysis from fetal mouse liver. Both the number of precursor cells triggered to proliferate and differentiate, and the size of the erythropoietic colonies formed, are directly dependent upon the concentration of erythropoietin included in the culture.

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References

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