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. 1974 Jun;71(6):2466-9.
doi: 10.1073/pnas.71.6.2466.

Prolongation of the life-span in mice adapted to large amounts of L-dopa

G C Cotzias, S T Miller, A R Nicholson Jr, W H Maston, L C Tang

Prolongation of the life-span in mice adapted to large amounts of L-dopa

G C Cotzias et al. Proc Natl Acad Sci U S A. 1974 Jun.

Abstract

Various concentrations of L-dopa (levodopa, L-3,4-dihydroxyphenylalanine) were incorporated in the diets of young male Swiss albino mice, and the highest concentrations to which these mice became adapted within 3 weeks were determined. One such concentration administered indefinitely eventually induced a youthful appearance, a significantly prolonged life-span, but also corneal opacities compatible with traumatic or chemical keratitis.

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References

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