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. 1974 Oct;71(10):3863-5.
doi: 10.1073/pnas.71.10.3863.

Solutions to the cost-of-selection dilemma

V Grant, R H Flake

Solutions to the cost-of-selection dilemma

V Grant et al. Proc Natl Acad Sci U S A. 1974 Oct.

Abstract

There are various biologically realistic ways around the cost-of-selection restriction on rapid multiple-gene substitution. Some of these ways depend upon particular forms of interaction or linkage in the genes undergoing substitution; other ways depend on particular conditions of population size and structure. The special genotypic and populational conditions required for rapid evolutionary change in genetically complex characters are not unusual in higher organisms.

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References

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