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. 1979 May;26(2):319-24.
doi: 10.1016/S0006-3495(79)85251-0.

K+ conductance modified by a titratable group accessible to protons from the intracellular side of the squid axon membrane

E Wanke, E Carbone, P L Testa

K+ conductance modified by a titratable group accessible to protons from the intracellular side of the squid axon membrane

E Wanke et al. Biophys J. 1979 May.

Abstract

In the range of pH examined (5.2-10), variations of internal pH from high to low values result in a reversible decrease of the conductance of the open K channels, without significantly affecting the kinetics parameters. A linear plot of the conductance versus internal pH suggests the existence of a titratable group that has an apparent pKa of about 6.9, and that is accessible to protons only from the intracellular side of the membrane.

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References

    1. J Physiol. 1952 Aug;117(4):500-44 - PubMed
    1. J Physiol. 1956 Feb 28;131(2):341-76 - PubMed
    1. Science. 1978 Jun 30;200(4349):1494-6 - PubMed
    1. J Membr Biol. 1978 Nov 8;43(4):295-315 - PubMed
    1. J Gen Physiol. 1974 Dec;64(6):666-90 - PubMed

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