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. 1973 Aug 3;181(4098):448-9.
doi: 10.1126/science.181.4098.448.

Virus-free adenocarcinoma of the frog (summer phase tumor) transcribes Lucké tumor herpesvirus-specific RNA

Virus-free adenocarcinoma of the frog (summer phase tumor) transcribes Lucké tumor herpesvirus-specific RNA

W Collard et al. Science. .

Abstract

[(3)H]RNA isolated from "virus-free," summer phase, renal adenocarcinomas of Rana pipiens labeled with [(3)H]uridine hybridizes with DNA of herpesvirus particles isolated from the winter phase Lucké tumor. Transcription of the herpesvirus genome in virus-free tumors provides additional evidence for the viral etiology of this tumor.

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