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. 1974 Nov 1;140(5):1432-7.
doi: 10.1084/jem.140.5.1432.

Genetic correlation of a mouse light chain variable region marker with a thymocyte surface antigen

P D Gottlieb

Genetic correlation of a mouse light chain variable region marker with a thymocyte surface antigen

P D Gottlieb. J Exp Med. .

Abstract

The inbred and congenic strain distribution of the I(H)-peptide marker in the variable region of mouse immunoglobulin light chains has been compared with other known genetic markers. A positive correlation was noted between the I(H)-peptide marker and expression of the Ly-3.1 thymocyte cell surface antigen. This suggests that the locus responsible for I(H)-peptide expression is genetically linked to the Ly-2 and Ly-3 loci in linkage group XI on chromsome 6 of the mouse.

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