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. 1972 Feb;22(2):227-30.

Immunosuppressive effect of male mouse submandibular gland extracts on plaque-forming cells in mice: abolition by orchiectomy

P A Kongshavn, W S Lapp

Immunosuppressive effect of male mouse submandibular gland extracts on plaque-forming cells in mice: abolition by orchiectomy

P A Kongshavn et al. Immunology. 1972 Feb.

Abstract

The plaque-forming response to sheep red blood cells is suppressed in mice treated with crude saline extracts of normal male mouse submandibular glands. Extracts from adult male mice orchiectomized at 2 weeks of age are ineffective, suggesting that the presence of this suppressive substance in the male mouse submandibular gland is testosterone-dependent.

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References

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