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. 1972 Feb;69(2):499-504.
doi: 10.1073/pnas.69.2.499.

Bacteriophage T7 DNA replication: a linear replicating intermediate (gradient centrifugation-electron microscopy-E. coli-DNA partial denaturation)

Bacteriophage T7 DNA replication: a linear replicating intermediate (gradient centrifugation-electron microscopy-E. coli-DNA partial denaturation)

J Wolfson et al. Proc Natl Acad Sci U S A. 1972 Feb.

Abstract

The T7 chromosome in the first round of replication is a Y-shaped DNA rod. Thus, it differs from previously observed bacterial and viral replicating chromosomes that are circular.

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References

    1. J Biol Chem. 1971 Nov 25;246(22):6874-9 - PubMed
    1. J Virol. 1967 Aug;1(4):779-92 - PubMed
    1. J Mol Biol. 1969 Aug 14;43(3):631-43 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1953;18:123-31 - PubMed
    1. Science. 1969 Mar 21;163(3873):1343-8 - PubMed

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