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. 1972 Apr;69(4):907-11.
doi: 10.1073/pnas.69.4.907.

Infection of Escherichia coli by T2 and T4 bacteriophages as seen in the electron microscope: T4 head morphogenesis

L D Simon

Infection of Escherichia coli by T2 and T4 bacteriophages as seen in the electron microscope: T4 head morphogenesis

L D Simon. Proc Natl Acad Sci U S A. 1972 Apr.

Abstract

Bacteriophage T4 capsids seem to be assembled on E. coli protoplasmic membranes. This process seems to involve "lumps" of head protein, which convert to tau particles, which in turn give rise to empty heads. The empty heads leave the bacterial membrane and are then filled with DNA in the central region of the cell. T4 gene 16 and 17 products appear to be necessary for head filling.

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References

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