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. 1972 May;69(5):1188-91.
doi: 10.1073/pnas.69.5.1188.

Sedimentation properties of yeast chromosomal DNA

T D Petes, W L Fangman

Sedimentation properties of yeast chromosomal DNA

T D Petes et al. Proc Natl Acad Sci U S A. 1972 May.

Abstract

Sedimentation analysis of nuclear DNA released from spheroplasts of the yeast Saccharomyces cerevisiae indicates that it has a number average molecular weight of 6.2 x 10(8). The chromosomal DNA molecules range in size from as small as 5 x 10(7) daltons to as large as 1.4 x 10(9) daltons. Based on these values and estimates of the total DNA content of the yeast nucleus, it is proposed that each yeast chromosome contains a single DNA duplex.

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References

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