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. 1972 Jun;69(6):1583-6.
doi: 10.1073/pnas.69.6.1583.

Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions

F K Stephan, I Zucker

Circadian rhythms in drinking behavior and locomotor activity of rats are eliminated by hypothalamic lesions

F K Stephan et al. Proc Natl Acad Sci U S A. 1972 Jun.

Abstract

Bilateral electrolytic lesions in the suprachiasmatic nuclei permanently eliminated nocturnal and circadian rhythms in drinking behavior and locomotor activity of albino rats. The generation of 24-hr behavioral rhythms and the entrainment of these rhythms to the light-dark cycle of environmental illumination may be coordinated by neurons in the suprachiasmatic region of the rat brain. Destruction of the medial preoptic area had no effect on 24-hr drinking rhythms.

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References

    1. Am J Physiol. 1971 Sep;221(3):711-8 - PubMed
    1. Physiol Behav. 1971 Feb;6(2):115-26 - PubMed
    1. Physiol Behav. 1972 Feb;8(2):315-26 - PubMed

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