Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Jun 1;94(2):101-8.
doi: 10.1016/0009-8981(79)90001-9.

Fetal tissue amino acid concentrations in argininosuccinic aciduria and in "maternal homocystinuria"

D K Rassin, L D Fleisher, A Muir, R J Desnick, G E Gaull

Fetal tissue amino acid concentrations in argininosuccinic aciduria and in "maternal homocystinuria"

D K Rassin et al. Clin Chim Acta. .

Abstract

Free amino acid concentrations have been measured in the tissues of a fetus at risk for argininosuccinic aciduria and of an obligate heterozygous fetus in a mother homozygous for homocystinuria. Argininosuccinic acid was detected in all tissues studied of the homozygous affected fetus from the heterozygous mother. Abnormal concentrations of methionine and cystathionine were observed in the tissues of the fetus who was an obligate heterozygote for homocystinuria. These abnormal free amino acid concentrations occur early in fetal development and may be related to later brain dysfunction.

PubMed Disclaimer

Publication types

LinkOut - more resources