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. 1972 Jun;13(6):427-9.
doi: 10.1136/gut.13.6.427.

Cell-mediated immune reactivity in liver disease

P A Bacon, H Berry, R Bown

Cell-mediated immune reactivity in liver disease

P A Bacon et al. Gut. 1972 Jun.

Abstract

Cell-mediated immunity has been investigated using the leucocyte migration test in 32 patients with chronic active hepatitis or primary biliary cirrhosis. Twenty-six (75%) showed reactivity to liver extract. At least two antigens are involved. Cell-mediated reactivity was confirmed in some cases using lymphocyte ;blast' transformation. There was no correlation with the presence of auto-antibodies.Cell-mediated immunity to parotid extract was shown in 10 cases (28%). This is in accord with the occurrence of the sicca syndrome in liver disease, which has been confirmed in this study.

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