Class, subclass, and allelic exclusion of membrane-bound Ig of human B lymphocytes
- PMID: 4557774
- PMCID: PMC2139201
- DOI: 10.1084/jem.136.2.409
Class, subclass, and allelic exclusion of membrane-bound Ig of human B lymphocytes
Abstract
Membrane-bound immunoglobulins of peripheral blood B lymphocytes and of lymphocytes from an IgG chronic lymphocytic leukemia showed restriction to one immunoglobulin class, one IgG subclass, and one Gm allotype. Certain antigens in the C-terminal part of IgG Fc were not exposed on the cell surface.
