[Significance of the complement system in acute pancreatitis in rats]
- PMID: 456145
[Significance of the complement system in acute pancreatitis in rats]
Abstract
The influence of complement system in acute pancreatitis in the rat was examined. Two different experimental procedures were used to induce pancreatitis: distal choledochal ligature and the Pfeffer model as modified by NEVALAINEN. In both procedures an acute pancreatitis developed and complement depression was noted. These results showed that consumption of complement will occur even in pancreatitis induced by other than immunologic models. In a second series the same experimental procedures were used in rats that had been decomplemented by application of cobra venom factor. It was possible to produce an acute pancreatitis of moderate severity.
Similar articles
-
[The role of the complement system in experimental pancreatitis (author's translation)].Langenbecks Arch Chir. 1980;353(1):9-17. doi: 10.1007/BF01261794. Langenbecks Arch Chir. 1980. PMID: 6163058 German.
-
The serum complement system--a mediator of acute pancreatitis.Virchows Arch A Pathol Anat Histol. 1975;365(3):193-9. doi: 10.1007/BF00434038. Virchows Arch A Pathol Anat Histol. 1975. PMID: 804750
-
The possible role of serum complement system in the formal pathogenesis of acute pancreatitis II. Cobra venom factor pancreatitis--sodiumtaurocholate and deoxycholate pancreatitis.Acta Hepatogastroenterol (Stuttg). 1975 Oct;22(5):335-46. Acta Hepatogastroenterol (Stuttg). 1975. PMID: 128273 Review. No abstract available.
-
Effect of complement depletion on the induction of amebic liver abscess in the hamster.Arch Invest Med (Mex). 1980;11(1 Suppl):173-80. Arch Invest Med (Mex). 1980. PMID: 7469638
-
Complement depletion with humanised cobra venom factor: efficacy in preclinical models of vascular diseases.Thromb Haemost. 2015 Mar;113(3):548-52. doi: 10.1160/TH14-04-0300. Epub 2014 Jul 17. Thromb Haemost. 2015. PMID: 25031089 Review.