Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1972 Sep;6(3):384-9.
doi: 10.1128/iai.6.3.384-389.1972.

Detection of delayed hypersensitivity in mice injected with ribonucleic acid-protein fractions of Salmonella typhimurium

R A Smith, N J Bigley

Detection of delayed hypersensitivity in mice injected with ribonucleic acid-protein fractions of Salmonella typhimurium

R A Smith et al. Infect Immun. 1972 Sep.

Abstract

Manifestations of delayed hypersensitivity (cell-mediated immunity) were found to be present in mice immunized with virulent Salmonella typhimurium SR-11 subfractions which contained appreciable concentrations of bacterial protein and in mice immunized with the living, attenuated RIA strain of S. typhimurium. Delayed hypersensitive responses were measured by footpad sensitivity in the immunized mice and in vitro by inhibition of spleen cell migration and by increase in (3)H-thymidine uptake by lymphoid cell populations when exposed to bacterial fractions rich in protein content.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Infect Immun. 1971 Oct;4(4):374-80 - PubMed
    1. Cell Immunol. 1972 Mar;3(3):501-15 - PubMed
    1. Br Med Bull. 1967 Jan;23(1):52-4 - PubMed
    1. J Immunol. 1970 Dec;105(6):1453-8 - PubMed
    1. Infect Immun. 1971 Oct;4(4):381-7 - PubMed

MeSH terms