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. 1973 Jan 5;179(4068):82-4.
doi: 10.1126/science.179.4068.82.

Insulin release by emiocytosis: demonstration with freeze-etching technique

Insulin release by emiocytosis: demonstration with freeze-etching technique

L Orci et al. Science. .

Abstract

The technique of freeze-etching for electron microscopy applied to isolated islets of Langerhans has permitted a successful evaluation of emiocytotic events on the cell surface. The frequency of these events in stimulated cells suggests that emiocytosis represents a significant mechanism for insulin release.

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