Temperature-sensitive mutation in regulation of ribonucleic acid synthesis in Escherichia coli
- PMID: 4565532
- PMCID: PMC251543
- DOI: 10.1128/jb.112.3.1150-1156.1972
Temperature-sensitive mutation in regulation of ribonucleic acid synthesis in Escherichia coli
Abstract
An Escherichia coli mutant dependent on exogenous transfer ribonucleic acid (RNA) for bulk RNA formation at 42 C has been isolated, starting from a parental strain permeable to RNA. In the absence of added transfer RNA at the high temperature, protein synthesis stopped, and the strain formed little if any ribosomal RNA.
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