Effect of elevated temperatures on protein synthesis in Escherichia coli
- PMID: 4565533
- PMCID: PMC251546
- DOI: 10.1128/jb.112.3.1177-1183.1972
Effect of elevated temperatures on protein synthesis in Escherichia coli
Abstract
Upon a temperature shift from 30 C to 42 to 44 C, Escherichia coli experiences a transient slowdown in rate of optical density increase, uridine incorporation, and amino acid incorporation. The data show that the primary target for thermal inactivation is a molecule(s) required for the initiation of protein synthesis. The effect on ribonucleic acid synthesis is a secondary effect.
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