Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1973 Jan;70(1):156-60.
doi: 10.1073/pnas.70.1.156.

Colicin E3: a unique endoribonuclease

B Meyhack, I Meyhack, D Apirion

Colicin E3: a unique endoribonuclease

B Meyhack et al. Proc Natl Acad Sci U S A. 1973 Jan.

Abstract

The question of whether or not a cellular ribonuclease is involved in the cleavage of 16S ribosomal RNA by colicin E3 was investigated. For this purpose ribosomes from strains devoid of some ribonucleases or ribosomes in which ribonucleases had been inactivated by heat or removed by extensive washings were used for the colicin reaction. Since the 16S RNA of all these different ribosomes, and even of the most extensively washed ribosomes, was cleaved by colicin E3, it is suggested that cellular ribonucleases are not involved in colicin E3 action. Thus, colicin E3 seems to be a unique endoribonuclease.

PubMed Disclaimer

References

    1. J Mol Biol. 1966 Mar;16(1):67-84 - PubMed
    1. Biochem J. 1965 Sep;96(3):671-80 - PubMed
    1. FEBS Lett. 1972 Apr 15;22(1):73-75 - PubMed
    1. Nat New Biol. 1971 Dec 1;234(48):133-7 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 May;68(5):964-8 - PubMed

MeSH terms

LinkOut - more resources