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. 1972 Dec;12(4):429-38.

The effect of thyroid antigens on the in vitro migration of leucocytes from patients with Hashimoto thyroiditis

E A Calder, D McLeman, E W Barnes, W J Irvine

The effect of thyroid antigens on the in vitro migration of leucocytes from patients with Hashimoto thyroiditis

E A Calder et al. Clin Exp Immunol. 1972 Dec.

Abstract

A total of fifty-two patients with Hashimoto thyroiditis were tested for delayed hypersensitivity to thyroid antigens using the leucocyte migration test. The percentage of patients showing abnormal migration in the presence of crude thyroid extract, thyroglobulin, thyroid mitochondria and thyroid microsomes was 75, 44, 54 and 34% respectively. Fifty-three control patients were studied concurrently with the same antigens and the percentage showing abnormal migration was 4, 6, 6 and 6% respectively. The antigenic activity of the mitochondrial fraction was not organ specific; both liver and kidney mitochondria interfered with the migration of leucocytes from patients with Hashimoto thyroiditis.

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References

    1. Lancet. 1958 Nov 15;2(7055):1027-33 - PubMed
    1. J Exp Med. 1969 Aug 1;130(2):263-85 - PubMed
    1. Lancet. 1970 Jul 25;2(7665):163-8 - PubMed
    1. Acta Med Scand. 1968 Jan-Feb;183(1-2):101-5 - PubMed
    1. Lancet. 1957 Nov 16;273(7003):976-9 - PubMed

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