Comparative Study
doi: 10.1016/s0304-3835(77)80028-1.
The deficiency of cyclic AMP responsive G1 controls in cultured malignant liver epithelial cells
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- PMID: 45726
- DOI: 10.1016/s0304-3835(77)80028-1
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Comparative Study
The deficiency of cyclic AMP responsive G1 controls in cultured malignant liver epithelial cells
Cancer Lett.
1977 Mar.
Abstract
Normal rat liver epithelial cells in culture were blocked outside the S phase by dibutyryl cyclic AMP while malignant rat liver epithelial cells were slowed in S phase. It is suggested that this lack of normal response to a growth inhibitory factor by malignant cells may underly their relatively autonomous growth behavior.
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