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Clinical Trial
. 1973 Apr;48(4):286-90.
doi: 10.1136/adc.48.4.286.

Comparative trial of 2 weeks and 8 weeks cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood

T M Barratt, J S Cameron, C Chantler, C S Ogg, J F Soothill
Clinical Trial

Comparative trial of 2 weeks and 8 weeks cyclophosphamide in steroid-sensitive relapsing nephrotic syndrome of childhood

T M Barratt et al. Arch Dis Child. 1973 Apr.

Abstract

A comparative trial of 2 weeks and 8 weeks cyclophosphamide therapy given during steroid-maintained remission in 32 children with steroid-sensitive relapsing nephrotic syndrome of childhood is reported. A significantly greater number of the 16 children who received 2 weeks therapy relapsed after steroid withdrawal than of those who received 8 weeks therapy. Relapses occurred later after 2 weeks cyclophosphamide therapy than in our previous experience of steroid treatment alone.

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References

    1. Lancet. 1970 Sep 5;2(7671):479-82 - PubMed
    1. Lancet. 1972 Mar 11;1(7750):568-9 - PubMed

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