Enhanced immune response after immunosuppression by Streptococcal pyrogenic exotoxin
- PMID: 4577414
- PMCID: PMC422796
- DOI: 10.1128/iai.7.6.1009-1011.1973
Enhanced immune response after immunosuppression by Streptococcal pyrogenic exotoxin
Abstract
Streptococcal pyrogenic exotoxin (SPE) was shown previously to be a potent immunosuppressant. This paper presents data documenting that immunosuppression frequently was followed by elevated antibody and plaque-forming cell levels as noted in our earlier report. The data are interpreted as a differential effect of SPE upon suppressor T cells and secreting B cells.
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