Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1973 Jul;70(7):2046-50.
doi: 10.1073/pnas.70.7.2046.

A genetic method for determining the order of events in a biological pathway

J Jarvik, D Botstein

A genetic method for determining the order of events in a biological pathway

J Jarvik et al. Proc Natl Acad Sci U S A. 1973 Jul.

Abstract

We describe the application of a simple genetic test that indicates the order of events in a morphogenic or biochemical pathway. The test uses temperature-sensitive (ts) and cold-sensitive (cs) mutants, and it orders the times at which the ts and cs defects are expressed.

PubMed Disclaimer

References

    1. J Bacteriol. 1969 Mar;97(3):1298-304 - PubMed
    1. Virology. 1972 Jul;49(1):268-82 - PubMed
    1. Genetics. 1971 Jan;67(1):5-17 - PubMed
    1. Mutat Res. 1968 Jul-Aug;6(1):1-14 - PubMed
    1. Proc Natl Acad Sci U S A. 1965 Aug;54(2):451-7 - PubMed

LinkOut - more resources