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. 1973 Nov 29;289(22):1155-9.
doi: 10.1056/NEJM197311292892201.

Recovery from "hepatorenal syndrome" after orthotopic liver transplantation

S Iwatsuki, M M Popovtzer, J L Corman, M Ishikawa, C W Putnam, F H Katz, T E Starzl

Recovery from "hepatorenal syndrome" after orthotopic liver transplantation

S Iwatsuki et al. N Engl J Med. .

Abstract

Three patients with progressive renal failure and advanced hepatic insufficiency due to cirrhosis of the liver underwent orthotopic liver transplantation. All three patients had immediate improvement in hepatic function and within two weeks after liver replacement regained nearly normal kidney function. However, the renal recovery was delayed in each case, and its course was not uniform. Plasma renin activity was high, and renin substrate was low before transplantation in one case in which these measurements were obtained; both returned to normal soon after liver replacement.

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Figures

Figure 1
Figure 1
Renal Function and Bilirubin in Cases 1–3 before and after Orthotopic Liver Transplantation.
Figure 2
Figure 2
Serum and Urinary Sodium and Prothrombin Time (per Cent of Control) in Cases 1–3 before and after Orthotopic Liver Transplantation.
See this image and copyright information in PMC

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