Tissue-specific transcription of the globin gene in isolated chromatin
- PMID: 4587253
- PMCID: PMC427254
- DOI: 10.1073/pnas.70.12.3440
Tissue-specific transcription of the globin gene in isolated chromatin
Abstract
RNA was transcribed from chrmation from mouse fetal liver or brain, by use of DNA-dependent RNA polymerase of Escherichia coli. Globin messenger RNA sequences in the transcript were measured with complementary DNA copied from globin messenger RNA with RNA-dependent DNA polymerase. Globin messenger RNA sequences were found in RNA newly transcribed from chromatin from erythropoietic tissue but not in that transcribed from brain chromatin.
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