doi: 10.1021/jm00191a026.
Synthesis of a proposed thymic factor
- PMID: 458811
- DOI: 10.1021/jm00191a026
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Synthesis of a proposed thymic factor
J Med Chem.
1979 May.
Abstract
Less than Glu-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn, a proposed serum thymic factor, has been synthesized. The protected precursor, less than Glu-Ala-Lys(i-Noc)-ser(Bzl)-Gln-Gly-Gly-Ser(Bzl)-Asn, was prepared by a combination of solid phase and solution methods. The benzyl blocking groups were removed by HF and the i-Noc blocking group was removed by catalytic hydrogenation.
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