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. 1974 Feb 8;183(4124):520-1.
doi: 10.1126/science.183.4124.520.

Toxaphene insecticide: a complex biodegradable mixture

J E Casida, R L Holmstead, S Khalifa, J R Knox, T Osawa, K J Palmer, R Y Wong
Free article

Toxaphene insecticide: a complex biodegradable mixture

J E Casida et al. Science. .
Free article

Abstract

Adsorption and gas-liquid chromatography separate toxaphene into at least 175 polychlorinated 10-carbon compounds including Cl(6), Cl(7), Cl(8), Cl(9), and Cl(10) derivatives. One toxic component is 2,2,5-endo,6-exo,8,9,10-heptachlorobornane. Rats metabolically dechlorinate toxaphene, removing about half of the chlorine from the technical insecticide and from each of seven subfractions of varying composition and toxicity.

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