Characterization of aminoacyl transfer ribonucleic acid formation stimulated by polyamines
- PMID: 4591475
- PMCID: PMC251232
- DOI: 10.1128/jb.111.1.1-6.1972
Characterization of aminoacyl transfer ribonucleic acid formation stimulated by polyamines
Abstract
From a comparative study of aminoacyl transfer ribonucleic acid (tRNA) formation stimulated by polyamines or by Mg(2+), it is shown that both reactions have the same requirements for adenosine triphosphate, tRNA, and aminoacyl-tRNA synthetase. Reaction kinetics are similar in both reactions. The same tRNA is aminoacylated in the presence of either spermine of Mg(2+). Aminoacyl-tRNA formed in the presence of polyamines can be a donor of amino acids in polypeptide synthesis.
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