Autolysis of microbial cells: salt activation of autolytic enzymes in a mutant of Staphylococcus aureus
- PMID: 4591480
- PMCID: PMC251268
- DOI: 10.1128/jb.111.1.272-283.1972
Autolysis of microbial cells: salt activation of autolytic enzymes in a mutant of Staphylococcus aureus
Abstract
The effect of various salts on the autolysis of cell wall of a ribitol teichoic acid-deficient mutant of Staphylococcus aureus H (strain 52A5 carrying tar-1) was compared with the parent strain. In the presence of high concentrations of certain salts such as 1.0 m NaCl, the mutant undergoes autolysis with the release of osmotically sensitive spheroplasts. The parent strain is not affected by these conditions. The stimulation of lysis is related to an activation of N-acylmuramyl-l-alanine amidase.
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