Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1972 Jul;111(1):7-14.
doi: 10.1128/jb.111.1.7-14.1972.

Loss of R factors promoted by bacteriophage M13 and the M13 carrier state

S E Russell, V N Iyer

Loss of R factors promoted by bacteriophage M13 and the M13 carrier state

S E Russell et al. J Bacteriol. 1972 Jul.

Abstract

The infection of different Hfr strains of Escherichia coli bearing derepressed R factors of the fi(+) or fi(-) type can result in the loss of the R factor and the conversion of the infected cells to the R(-) state. This extends earlier observations on the elimination of F' factors by bacteriophage M13 infection. Variability in the efficiency of this conversion can arise because of genetic factors independent of the R factor being eliminated. A fraction of the infected but unconverted R(+) cells were M13 carrier strains. The carrier state had an intracellular basis, and single R(+) cells could maintain the carrier state.

PubMed Disclaimer

References

    1. J Mol Biol. 1965 Jul;12(3):641-6 - PubMed
    1. Genet Res. 1966 Feb;7(1):134-40 - PubMed
    1. Proc Natl Acad Sci U S A. 1965 Dec;54(6):1713-20 - PubMed
    1. Genetics. 1966 Jul;54(1):61-76 - PubMed
    1. Proc Natl Acad Sci U S A. 1966 Jul;56(1):126-32 - PubMed

MeSH terms

LinkOut - more resources