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Clinical Trial
. 1974 Mar 9;1(5905):436-40.
doi: 10.1136/bmj.1.5905.436.

A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction

P C Elwood, A L Cochrane, M L Burr, P M Sweetnam, G Williams, E Welsby, S J Hughes, R Renton
Clinical Trial

A randomized controlled trial of acetyl salicylic acid in the secondary prevention of mortality from myocardial infarction

P C Elwood et al. Br Med J. .

Abstract

The results of a randomized controlled trial of a single daily dose of acetyl salicylic acid (aspirin) in the prevention of reinfarction in 1,239 men who had had a recent myocardial infarct were statistically inconclusive. Nevertheless, they showed a reduction in total mortality of 12% at six months and 25% at twelve months after admission to the trial. Further trials are urgently required to establish whether or not this effect is real.

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References

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