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. 1974 Apr 20;2(5911):145-9.
doi: 10.1136/bmj.2.5911.145.

Assessment of coagulation and fibrinolysis in pre-eclampsia

S M Wood, D Burnett, A M Picken, G W Farrell, P Wolf

Assessment of coagulation and fibrinolysis in pre-eclampsia

S M Wood et al. Br Med J. .

Abstract

A method is described for distinguishing coagulation from fibrinolysis by three estimates of fibrinogen. This "fibrinogen series" together with plasma antithrombin and urinary urokinase have been compared in pregnant patients with venous thrombosis and pre-eclampsia. Evidence is presented for active coagulation during deterioration of the pre-eclampsia state and for enhanced fibrinolysis during improvement.

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