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. 1974 May 1;139(5):1354-60.
doi: 10.1084/jem.139.5.1354.

Cellular requirements for the primary in vitro antibody response to DNP-ficoll

Cellular requirements for the primary in vitro antibody response to DNP-ficoll

D E Mosier et al. J Exp Med. .

Abstract

The cellular requirements for the primary in vitro IgM and IgG response to dinitrophenyl-substituted Ficoll were examined. Neither thymus-derived lymphocytes nor macrophage-rich splenic adherent cells were required for anti-DNP antibody synthesis. DNP-Ficoll is therefore tentatively classified as a "thymic-independent" antigen.

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References

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