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Clinical Trial
. 1974 May 11;2(5914):304-6.
doi: 10.1136/bmj.2.5914.304.

Gastric response to metiamide

B Thjodleifsson, K G Wormsley
Clinical Trial

Gastric response to metiamide

B Thjodleifsson et al. Br Med J. .

Abstract

Metiamide greatly reduced pentagastrin-stimulated and overnight secretion of acid and pepsin in 11 patients with duodenal ulcer and virtually abolished gastric secretion in three patients with gastric ulcer. The drug was equally effective when infused intravenously or intraduodenally. A therapeutic trial of Metiamide is warranted in diseases caused or aggravated by excess gastric secretion of acid and pepsin.

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References

    1. Gastroenterology. 1973 Jan;64(1):1-11 - PubMed
    1. Gut. 1973 May;14(5):424 - PubMed
    1. Biochem J. 1948;42(1):104-9 - PubMed

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