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. 1972 Sep;23(3):283-7.

Influence of vitamin A on immunological response

M Jurin, I F Tannock

Influence of vitamin A on immunological response

M Jurin et al. Immunology. 1972 Sep.

Abstract

The influence of vitamin A injections on immunological response in mice was investigated. Two end-points were used: the titre of haemagglutinin at 10 or 15 days after sensitization with sheep red blood cells (SRBC), and the time to reject C57BL/6 male skin grafts by isologous female recipients. Daily vitamin A injections for the 5 days preceding or following sensitization with SRBC led to a large increase in the production of haemagglutinin antibodies. Injection of vitamin A for the 5 days preceding or following grafting, or starting on the 6th day after grafting, significantly reduced the mean rejection time of male skin grafts.

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