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. 1974 Dec;14(6):1630-2.
doi: 10.1128/JVI.14.6.1630-1632.1974.

Class of phi chi 174 mutants relatively deficient in synthesis of viral RNA

J B Clements, R L Sinsheimer

Class of phi chi 174 mutants relatively deficient in synthesis of viral RNA

J B Clements et al. J Virol. 1974 Dec.

Abstract

Nonpermissive cells infected with phiX174 gene D amber mutants synthesized some sixfold less viral RNA than permissive cells. The decrease was unaffected by increasing the multiplicity of infection and was a consequence of an overall decrease in all viral RNA species. It is suggested that the gene D product may function in replicative form DNA unwinding to expose the template for transcription.

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References

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