Isolation of the lysozyme gene of chicken
- PMID: 461199
- PMCID: PMC327884
- DOI: 10.1093/nar/6.8.2667
Isolation of the lysozyme gene of chicken
Abstract
The lysozyme gene has been purified by molecular cloning from two chicken gene libraries. Several recombinant phages harbouring sequences homologous to a plasmid carrying a double stranded lysozyme cDNA have been isolated. One recombinant appears to carry an entire lysozyme gene. Electron microscopic studies show that the latter is split by at least three introns. The length of the gene is about 3.9 kb, 6 times longer than lysozyme mRNA.
Similar articles
-
Arrangement of coding and intervening sequences of chicken lysozyme gene.Proc Natl Acad Sci U S A. 1979 Dec;76(12):6196-200. doi: 10.1073/pnas.76.12.6196. Proc Natl Acad Sci U S A. 1979. PMID: 293713 Free PMC article.
-
Cloning of chicken lysozyme structural gene sequences synthesized in vitro.Nucleic Acids Res. 1978 Sep;5(9):3275-94. doi: 10.1093/nar/5.9.3275. Nucleic Acids Res. 1978. PMID: 568256 Free PMC article.
-
Isolation of recombinant plasmids bearing cDNA to hen ovomucoid and lysozyme mRNAs.J Biol Chem. 1979 Sep 25;254(18):9277-83. J Biol Chem. 1979. PMID: 383714
-
The chicken lysozyme locus as a paradigm for the complex developmental regulation of eukaryotic gene loci.J Biol Chem. 1997 Oct 17;272(42):26075-8. doi: 10.1074/jbc.272.42.26075. J Biol Chem. 1997. PMID: 9334168 Review. No abstract available.
-
The discovery of 'split' genes: a scientific revolution.Trends Biochem Sci. 1988 Mar;13(3):110-3. doi: 10.1016/0968-0004(88)90052-7. Trends Biochem Sci. 1988. PMID: 3072705 Review. No abstract available.
Cited by
-
Sequence organization of animal nuclear DNA.Hum Genet. 1980;55(1):1-18. doi: 10.1007/BF00329120. Hum Genet. 1980. PMID: 6256281 Review.
-
Arrangement of coding and intervening sequences of chicken lysozyme gene.Proc Natl Acad Sci U S A. 1979 Dec;76(12):6196-200. doi: 10.1073/pnas.76.12.6196. Proc Natl Acad Sci U S A. 1979. PMID: 293713 Free PMC article.
-
DNA organisation in the chicken lysozyme gene region.Nucleic Acids Res. 1981 Aug 11;9(15):3575-88. doi: 10.1093/nar/9.15.3575. Nucleic Acids Res. 1981. PMID: 6269085 Free PMC article.
-
Exons encode functional and structural units of chicken lysozyme.Proc Natl Acad Sci U S A. 1980 Oct;77(10):5759-63. doi: 10.1073/pnas.77.10.5759. Proc Natl Acad Sci U S A. 1980. PMID: 6934509 Free PMC article.
-
Transformation of mouse fibroblasts to methotrexate resistance by a recombinant plasmid expressing a prokaryotic dihydrofolate reductase.Proc Natl Acad Sci U S A. 1981 Mar;78(3):1527-31. doi: 10.1073/pnas.78.3.1527. Proc Natl Acad Sci U S A. 1981. PMID: 6262811 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources