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. 1974 Nov;144(2):265-75.
doi: 10.1042/bj1440265.

Biogenesis of mitchondria. Phospholipid synthesis in vitro by yeast mitochondrial and microsomal fractions

G S Cobon, P D Crowfoot, A W Linnane

Biogenesis of mitchondria. Phospholipid synthesis in vitro by yeast mitochondrial and microsomal fractions

G S Cobon et al. Biochem J. 1974 Nov.

Abstract

The ability in vitro of yeast mitochondrial and microsomal fractions to synthesize lipid de novo was measured. The major phospholipids synthesized from sn-[2-(3)H]glycerol 3-phosphate by the two microsomal fractions were phosphatidylserine, phosphatidylinositol and phosphatidic acid. The mitochondrial fraction, which had a higher specific activity for total glycerolipid synthesis, synthesized phosphatidylglycerol, phosphatidylethanolamine, phosphatidylinositol, phosphatidylserine and phosphatidic acid, together with smaller amounts of neutral lipids and diphosphatidylglycerol. Phosphatidylcholine synthesis from both S-adenosyl[Me-(14)C]methionine and CDP-[Me-(14)C]choline appeared to be localized in the microsomal fraction.

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References

    1. Biochem J. 1973 Aug;134(4):923-34 - PubMed
    1. Biochem J. 1973 Aug;134(4):935-47 - PubMed
    1. J Bioenerg. 1971 Dec;2(5):327-49 - PubMed
    1. Mol Gen Genet. 1974;128(1):43-54 - PubMed
    1. J Biol Chem. 1956 Sep;222(1):193-214 - PubMed

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