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. 1979 Apr-Jun;17(2):109-11.

Decrease of testosterone, cholesterol and ascorbic acid in the rat testis after administration of pineal polypeptides

E Damian, O Ianăş, I Bădescu
  • PMID: 462106

Decrease of testosterone, cholesterol and ascorbic acid in the rat testis after administration of pineal polypeptides

E Damian et al. Endocrinologie. 1979 Apr-Jun.

Abstract

Administration of 2 ml/day/animal, of melatonin-free pineal extract to the rat for three days induced a significant decrease in the testicular tissue concentration of testosterone, cholesterol and ascorbic acid. A dose of 1 microgram melatonin/day/animal given for 3 days did not alter these biochemical elements implied in testicular steroidogenesis.

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