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. 1975 Feb;11(2):290-3.
doi: 10.1128/iai.11.2.290-293.1975.

Antiglobulin factors in normal mouse serum reacting with enzyme-digested gamma globulin

J W Measel Jr, G C Cozad

Antiglobulin factors in normal mouse serum reacting with enzyme-digested gamma globulin

J W Measel Jr et al. Infect Immun. 1975 Feb.

Abstract

The presence of antiglobulin factors in normal mouse serum was studied. Mice were injected with human 0 Rh(+) erythrocytes and the resulting gamma globulins were digested with papain. The reaction was demonstrated by agglutinations of human 0 Rh (+) perythryocytes sensitized with the Fab fragments when treated with normal mouse serum. Studies suggested that there are two factors in mice, a 7S AND A 19S globulin form. Cross-reactivity between strains of mice was demonstrated.

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