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Comparative Study
. 1979 Aug 17;205(4407):696-8.
doi: 10.1126/science.462176.

4-aminobutyrate:2-oxoglutarate aminotransferase in blood platelets

Comparative Study

4-aminobutyrate:2-oxoglutarate aminotransferase in blood platelets

H L White. Science. .

Abstract

Platelet lysates obtained from blood of humans, dogs, and rats catalyzed the transamination of 4-aminobutyrate with 2-oxoglutarate as cosubstrate. Human platelet 4-aminobutyrate:2-oxoglutarate aminotransferase (36.5 +/- 3.2 picomoles per minute per milligram of platelet protein) resembled the brain enzyme in kinetic properties and in response to cofactors and inhibitors.

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