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. 1975 Jan;114(1 Pt 1):141-4.

Carrier-determined tolerance in vitro

P Galanaud, M Aldo-Benson, Y Borel
  • PMID: 46237

Carrier-determined tolerance in vitro

P Galanaud et al. J Immunol. 1975 Jan.

Abstract

A primary immune response to normal BDF1 spleen cells was obtained in vitro to the T-independent antigen TNP-T4 coliphage. This anti-TNP response was suppressed by exposing the spleen cells for 6 hr to TNP bound either to isologous or heterologous gamma-globulin. The suppression was hapten specific. In contrast, TNP-albumin conjugates did not induce tolerance in vitro.

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