Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1972 Aug;11(4):543-8.

Cytotoxic lymphocytes in Hashimoto's thyroiditis

W K Podleski

Cytotoxic lymphocytes in Hashimoto's thyroiditis

W K Podleski. Clin Exp Immunol. 1972 Aug.

Abstract

The ability of peripheral lymphocytes from patients with Hashimoto's disease to destroy target cells coated with thyroid-related-autoantigens has been demonstrated. Direct cytotoxicity was demonstrable against mouse mastocytoma target cells coated with human thyroglobulin or microsomal antigen from thyrotoxic thyroid glands. No correlation was noted between circulating antibody and the ability of these cells to be cytotoxic.

The significance of the in vitro expression of cell-mediated immunity in this method is discussed.

PubMed Disclaimer

References

    1. Br Med Bull. 1967 Jan;23(1):66-71 - PubMed
    1. Immunology. 1968 Feb;14(2):181-96 - PubMed
    1. Clin Exp Immunol. 1968 Feb;3(2):133-51 - PubMed
    1. Proc Soc Exp Biol Med. 1968 Dec;129(3):756-60 - PubMed
    1. J Immunol. 1970 Oct;105(4):919-27 - PubMed

LinkOut - more resources