Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1973 Jan;73(1):57-71.
doi: 10.1093/genetics/73.1.57.

Regulation of ribosomal RNA gene multiplicity in Drosophila melanogaster

K D Tartof

Regulation of ribosomal RNA gene multiplicity in Drosophila melanogaster

K D Tartof. Genetics. 1973 Jan.

Abstract

The ribosomal RNA (rRNA) genes of Drosophila melanogaster can undergo a disproportionate replication of their number. This occurs when the cluster of rRNA genes (rDNA) of one chromosome is maintained with a homologous chromosome that is completely or partially deficient in its rDNA. Under appropriate genetic conditions, it appears that disproportionate rDNA replication can be generated at the level of both somatic and germ line cells. In the latter case, mutants partially deficient for rDNA can increase their rRNA gene number to the wild type level and transmit this new genotype to successive generations.

PubMed Disclaimer

References

    1. Biochim Biophys Acta. 1966 Feb 21;114(2):296-310 - PubMed
    1. Genetics. 1966 Sep;54(3):819-34 - PubMed
    1. Genetics. 1969;61(1):Suppl:319-27 - PubMed
    1. Dev Biol. 1970 Jul;22(3):495-512 - PubMed
    1. J Mol Biol. 1970 Jul 28;51(2):171-83 - PubMed

LinkOut - more resources