Latex agglutination in the diagnosis of meningococcal meningitis
- PMID: 4632330
- PMCID: PMC477625
- DOI: 10.1136/jcp.25.12.1079
Latex agglutination in the diagnosis of meningococcal meningitis
Abstract
Group-specific polysaccharides of Neisseria meningitidis groups A and C have been demonstrated by means of a rapid, sensitive slide agglutination test with latex particles coated with antibodies. In this manner, the diagnosis can be made from the cerebrospinal fluid of patients with meningococcal meningitis caused by serogroups A or C even when the culture is negative. The method appears to be more sensitive than countercurrent immunoelectrophoresis and less elaborate.
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