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. 1972 Dec;25(12):1079-82.
doi: 10.1136/jcp.25.12.1079.

Latex agglutination in the diagnosis of meningococcal meningitis

W P Severin

Latex agglutination in the diagnosis of meningococcal meningitis

W P Severin. J Clin Pathol. 1972 Dec.

Abstract

Group-specific polysaccharides of Neisseria meningitidis groups A and C have been demonstrated by means of a rapid, sensitive slide agglutination test with latex particles coated with antibodies. In this manner, the diagnosis can be made from the cerebrospinal fluid of patients with meningococcal meningitis caused by serogroups A or C even when the culture is negative. The method appears to be more sensitive than countercurrent immunoelectrophoresis and less elaborate.

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References

    1. J Exp Med. 1969 Jun 1;129(6):1349-65 - PubMed
    1. J Clin Pathol. 1972 Jun;25(6):528-30 - PubMed
    1. N Engl J Med. 1971 Aug 19;285(8):434-6 - PubMed
    1. J Immunol. 1971 Feb;106(2):314-7 - PubMed
    1. Lancet. 1971 Sep 4;2(7723):519-21 - PubMed

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