Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1973 Jan;26(1):7-16.
doi: 10.1136/jcp.26.1.7.

Genus-specific leptospiral antigen and its possible use in laboratory diagnosis

A Palit, J Gulasekharam

Genus-specific leptospiral antigen and its possible use in laboratory diagnosis

A Palit et al. J Clin Pathol. 1973 Jan.

Abstract

Sheep red cells, sensitized with a genus-specific leptospiral substance extracted from a water leptospira, were preserved by freeze drying. The serological reactivity of the preparation was tested against a total of 41 sera from proven cases of human leptospirosis and 27 from proven cases of animal leptospirosis. The sensitized, freeze-dried red cells appeared to be a sensitive reagent for the detection of leptospiral antibodies by haemagglutination. The use of this reagent as a screening test for leptospiral diagnosis is discussed. In the reported haemagglutination test on human and rabbit antisera the findings suggested that only IgM (19S) antibodies took part in the reaction.

PubMed Disclaimer

References

    1. Proc Soc Exp Biol Med. 1965 Dec;120(3):786-9 - PubMed
    1. J Mol Biol. 1967 Feb 14;23(3):615-7 - PubMed
    1. Appl Microbiol. 1969 Jan;17(1):185 - PubMed
    1. Trans R Soc Trop Med Hyg. 1968;62(6):880-99 - PubMed
    1. Proc Soc Exp Biol Med. 1969 Jul;131(3):871-5 - PubMed

LinkOut - more resources